Diabetic Cardiomyopathy and Adiponectin

People with DM can develop heart dysfunction called diabetic cardiomyopathy [5]. This is characterized by dilation and hypertrophy of the myocardium, accompanied by systolic dysfunction and / or left ventricular diastolic and their presence is independent of ischemic heart disease or hypertension coexistence [7]. Although diabetic cardiomyopathy is a chronic subclinical condition [8], eventually leads to reduced elasticity of the matrix extracellular and decreased contractile function of the heart [9]. The association between development of diabetic cardiomyopathy and high glucose levels have significant effects on the expression, organization and components for modifying the extracellular matrix in the heart [4].